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Sepsis: A small RCT in patients with sepsis found that IV NAC (150 mg/kg bolus then 50 mg/kg over 4 hours) improved hepatosplanchnic perfusion, glutathione levels, and liver function markers
However, another randomized, double-blind, placebo-controlled trial in 181 patients with diabetic neuropathy found that oral supplementation with either 600 mg/day, 1,200 mg/day, or 1,800 mg/day of lipoic acid for five weeks significantly improved neuropathic symptoms (77)
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It is used to treat bacterial infections caused by anaerobic bacteria, including stomach, skin , gynecological, bone, joint, lower respiratory tract, brain, and heart infections
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