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For men who have struggled with overeating, constant hunger, or poor blood sugar control, GLP-1 therapy can be a game changer

Tirzepatide slowed gastric emptying may delay melatonin absorption, making it less effective at the start of treatment or after dose increases

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Madry, H., van Dijk, C

According to NICE guidelines (NG28), GLP-1 receptor agonists are typically considered when triple therapy is not effective, not tolerated or contraindicated for type 2 diabetes

Patients should seek urgent medical attention for severe or persistent abdominal pain, repeated vomiting, or signs of dehydration, as these may indicate pancreatitis or gallbladder disease