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Mitochondrial oxidative stress and respiratory dysfunctions in cancer cells may, therefore, lead to the activation of apoptotic signals by the release of apoptosis-inducing factors and proteins and subsequent activation of the caspases [17], [18], [19]
The final dosing schedule may change once the medicine is licensed but it is expected to follow the pattern based on trials data : Start at a low dose, which is gradually increased, similar to how other treatments are prescribed
At 5mg/mL, the 2.5mg starting dose equals 50 IU and the 5mg step equals 100 IU (full 1mL syringe)
Product ID:15538625
Journal of the ASEAN Foundation of Endocrine Societies
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