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AOD-9604 works by stimulating lipolysis, the breakdown of fats and triglycerides, and inhibiting lipogenesis, the formation of new fat

It plays a vital role in brain function and the production of DNA and red blood cells

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And by doing that, it helps preserve NAD + (key energy carrying molecule), SAM (universal methyl donor), and the downstream processes that depend on them

However, treatment decisions should always be individualized and medically supervised

Since mouse microbiome profiles often highly correlate with body weight and fat composition, this study was designed to test whether the cecal microbiomes of DIO mice treated with NNMTi and LD were comparable to the microbiomes of age-matched lean counterparts and distinct from microbiomes of DIO mice maintained on a high-fat Western diet (WD) or subjected to LD switch alone