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Additionally, tirzepatide suppresses glucagon secretion, slows gastric emptying, and promotes satiety through central nervous system pathways that regulate appetite

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Because of these limitations, there was a desire for a GLP-1 agonist that could be taken orally at any time of the day without any food or water restrictions

These constituents are thought to modulate the hypothalamic-pituitary-adrenal (HPA) axis, potentially reducing cortisol levels and helping the body manage stress