Compounds binding there can stabilise the active conformation without needing to mimic the full peptide-extracellular-domain interaction
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Neuroprotective Research Applications Studies in Journal of Neurochemistry explored DSIPs neuroprotective properties, demonstrating reduced oxidative stress markers in brain tissue, enhanced neuronal survival under stress conditions, improved synaptic function parameters, and protection against excitotoxic injury in research models
However, lipase levels exceeding 3 times the upper limit of normal, accompanied by severe epigastric pain radiating to the back, represent a potential pancreatitis emergency
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Pulmonary oxalate deposition associated with Aspergillus niger infection