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adults have taken or are currently taking GLP-1 medication specifically for weight loss

Common side effects include constipation, nausea, and vomiting, for instance

The study found that patients prescribed semaglutide drugs had a statistically elevated risk of developing NAION compared to patients taking other diabetes or weight-loss medications

Shared decision-making, gradual dose titration, patient education, and close monitoring are key strategies to mitigate adverse effects and improve satisfaction

Additional GWAS findings have revealed associations with specific single nucleotide polymorphisms (SNPs) in genes such as IL-2 receptor alpha (IL2RA), cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), the IL-2/IL-21 locus, natural killer group 2D (NKG2D), and Ikaros family zinc finger 4 (IKZF4)

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