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In StatPearls [Internet]
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Comparative protocols sometimes pair a copper-peptide arm against a free copper-salt arm to separate peptide-specific signaling from generic trace-mineral effects
Jiang, Y.-H., Jhang, J.-F., Ho, H.-C., Chiou, D.-Y
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However, diffusion of these small molecules across lipid bilayers is too rapid to allow accurate experimental quantification 31
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