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It wasnt jittery, exactly, but I did notice a definite increase in overall energy and awakeness (especially at a time when I usually start fading and thinking about what Im going to have for dinner)

10.1016/j.amjcard.2008.02.003 266 SugitaS.InomataM.KonoY.ShiroshitaH.EtohT.ShiraishiN.et al (2013)

At doses of 25 to 100 grams, IV vitamin C achieves plasma concentrations 100 to 500 times higher than those possible through oral administration

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7.3 Targeting FSP1/CoQ 10 pathway Intrastriatal administration of CoQ 10 showed higher efficacy in exerting neuroprotective effects than oral CoQ 10 delivery in a rat PD model, requiring 17,000 times lower dose (241)

n-3 polyunsaturated fatty acids: the potential role for supplementation in cancer