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This is a transformative milestone for Rhythm and reinforces our commitment to bringing meaningful therapies to patients living with rare MC4R pathway diseases. Clinical Findings Supporting Expanded Indication The approval was supported by positive data from the pivotal phase 3 TRANSCEND trial, which evaluated setmelanotide in 142 patients with acquired HO

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DOI: 10.1080/14656566.2024.2343092

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S., Cheng, Y., Del Giuduce, F., Eisenberg, M