They can play the role of GLP-1
The breadth of these effects is the point: the receptor does not appear to act through a single disease-specific mechanism but through a general increase in neuronal resilience
He continued to say that for people with B12 deficiency, parenteral supplementation (ie not through the mouth/digestive system) therefore is a useless and expensive treatment, and if you still want it the NHS should not pay for it, you should pay for it yourself
The approval was supported by results from the SURMOUNT-OSA trial that revealed Zepbound led to a significant reduction in the apnea-hypopnea index at 52 weeks compared to placebo in individuals who were and were not receiving PAP therapy
178 TrachoothamD.ZhouY.ZhangH.DemizuY.ChenZ.PelicanoH.et al (2006)
Research suggests that stimulation of melanocortin 4 receptors (MC4R) may reduce amyloid-beta accumulation, support synaptic activity, and improve markers linked to neuroprotection