Reconstituting too early: Only reconstitute a vial when you are ready to start using it
However, if you are ill, high doses of vitamin B12 that you might receive to treat a deficiency may cause some symptoms, such as: What to avoid while taking B12
According to FDA labeling, medication should not be used if it appears cloudy, contains particles, or shows visible changes in color or consistency (except for Bydureon, which becomes a suspension after mixing)
Hypokalemia (low potassium) In rare cases, excessive B12 therapy can affect potassium levels.
Heffernan MA, Jiang WJ, Thorburn AW, Ng FM
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