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The antioxidant activity of GSH intermediated via thiol (-SH) of its cysteine residue upon its interaction with ROS or electrophiles and the GSH oxidized to GSSG (oxidized Glutathione), the GSSG will reduce to GSH by Glutathione reductase (GR), the activity of GR is therefore very important to keep the antioxidant power of mammalian cells, while GSH/GSSG ratio is an indicator for redox balance in the cell
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Consequently, regular monitoring of micronutrient status is essential, with deficiencies addressed via nutritional fortification or supplementation strategies [5]
L-glutathione usually refers to the biologically relevant amino-acid configuration, often in reduced form
Patients recovering from surgeries, especially those involving the digestive tract, should closely monitor their B12 levels
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