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doi: 10.1016/j.clnu.2025.06.011
Potential benefits include: Additional weight loss in cases of inadequate surgical response or weight regain Enhanced glycemic control for persistent or recurrent type 2 diabetes Cardiovascular risk reduction in appropriate patients Improvement in obesity-related comorbidities (hypertension, dyslipidemia, sleep apnea) Non-invasive intervention avoiding revision surgery However, the combined approach carries specific risks that warrant careful consideration
Ethics declarations Financial Support The preparation of this manuscript was supported by funding from Health@InnoHK Initiative Fund of the Hong Kong Special Administrative Region Government (ITC RC/IHK/4/7) and Vincent and Lily Woo Foundation
Injection site reactions during dose escalation Dose escalation is a standard part of tirzepatide treatment
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