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Consistent with this, the mRNA and protein levels of Gss have no difference between 2 months and 8 months age, and decreased significantly in the testis of 16-month-old mice (Fig
98 One approach involves the autoregulated overexpression of key cell cycle regulators, 99,100 including CDK1, CDK4, CCNB1, and CCND1, which have been shown to induce 1520% proliferation of mature cardiomyocytes and improve post-MI outcomes
The clinical consequence ranges from local inflammation through to systemic hypersensitivity and antibody formation
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