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We identified that GLP-1R agonism reduced ethanol consumption, mitigated ethanol-induced upregulation of several liver metabolizing enzymes, including Cyp2e1 and also reduced Cyp2e1 independent of ethanol intake

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A 72-week trial carried out on Wegovy found that patients using the 7.2 mg maintenance dose achieved, on average, a change in body weight of 21% compared to 2.4% in the placebo group

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