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Symptoms of deficiency include fatigue, heart muscle weakness, low blood sugar, vomiting, and muscle weakness
In roughly 30 years
(B6, especially in the pyridoxine form, is one of the few B vitamins that can lead to toxicity when used in excess.) Threonine is also important to gut barrier integrity in the small intestine, and I have read some reports of it helping with minimizing reactions to gluten, although I have not studied this in great depth yet
If gallstones block your bile ducts, you can have a gallbladder attack
I brew my own though at 500-600mg/ml
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