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Another meta-analysis of 21 trials in overweight and obese individuals found small but significant reductions in body weight (approximately 0.75 kg), BMI, and body fat percentage compared to placebo

For a 6mm needle, a 45-degree angle reduces the effective depth to roughly 4mm

DOI: 10.1016/j.cbi.2020.108968 [Google Scholar] Mei J, Sun J, Wu J, Zheng X

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Together, these effects help prevent dangerous blood sugar spikes, particularly relevant for people managing type 2 diabetes or insulin resistance

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