Recent research suggests GLP-1 medications like Wegovy may unintentionally disrupt your circadian rhythm, the 24-hour biological cycle that determines when you feel alert or sleepy
GLP-1 RAs promote satiety, reduce hunger, and dampen reward responsivity, which conceptually could open a temporary low-drive window during which behavioral techniques such as stimulus control, self-monitoring, and structured eating routines become more achievable
They also noted that media attention surrounding Wegovy may have increased reporting of side effects, which could have influenced the results
The existing deficiencies obstructing the use of fluorescent probes as diagnostic markers for PD are low biocompatibility, poor BBB permeability, unstable fluorescence properties, and poor receptor selectivity (Sun et al., 2024) (Table 6)
GLP-1R-agonists regulate several inflammatory pathways, including cytokine production, oxidative stress, glucotoxicity, lypotoxicity and the recruitment of immune cells in several organs
Providers watch these changes closely because they affect nutrition, hydration, medication tolerance, weight management, and dose decisions