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For reconstitution protocols, see the Peptide Reconstitution Guide
H., Tashkandi, M
Over the past decades, several randomized clinical trials (RCTs) have shown that GLP-1 RAs improve cardiovascular outcomes in patients with type 2 DM (T2DM) who have established CVDs or are at risk, as well as in individuals with CKD [16,17,18,19]
CLINICAL TRIAL EVIDENCE FOR DUAL GLP-1/GLUCAGON RAs AND TRIPLE AGONISTS IN MASH Survodutide Survodutide, a weekly dual GLP-1/GCG agonist, was assessed in a phase 2 dose-finding trial (NCT04771273) including 293 individuals with histologically confirmed MASH and fibrosis stages F1-F3 [46]
Where to learn more For clinicians: seek continuing education on metabolic medicine, peptide pharmacology, and gutbrain interactions
A recent case report showed no harmful effects after a woman with type 2 diabetes took liraglutide (similar to semaglutide) during the first trimester of her pregnancy
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