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In addition to activation by initiator caspases, caspase-3 has been shown to be activated by staurosporine, a non-selective inhibitor of protein kinases (Chae et al., 2000
J., Newsome, P
(2022) This meta-analysis confirmed that microneedling consistently enhances treatment outcomes when combined with topical agents
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doi: 10.1038/nchembio807 37 TerziEMSviderskiyVOAlvarezSWWhitenGCPossematoR
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