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The dose tiers are wider apart in absolute milligrams, the optional intermediate steps add flexibility that semaglutide does not offer, and the maximum dose of 15 mg reflects the dual-receptor mechanism that requires higher absolute amounts to achieve full therapeutic effect
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They bind to GLP-1 receptors and activate them, providing the same benefits as the natural hormone but with a longer duration of action
For self-funded employers, the PBM manages the formulary, pricing, and utilization rules in collaboration with the employer, who has flexibility to shape how these medications are covered
The best GLP-1 medication depends on your individual health history
Circulation , 150 (22), 1777-1790
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