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276 Mice with POMC neuron-specific SEL1L depletion develop age-associated obesity and hyperphagia owing to POMC retention within the ER, suggesting that HRD1 complex-mediated ERAD functions in the development of monogenic obesity associated with impaired prohormone folding

41 Article Information Published Online: October 8, 2025

Safety Considerations and When Arm Injections May Not Be Ideal Arm injections are appropriate for most patients but may present challenges in certain situations: limited subcutaneous fat, difficulty self-administering, or history of lipohypertrophy in previous arm injection sites

10.1023/A:1026718308155 Mol

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Combination contraceptives: Effects on weight