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Above 40 mg/day, the risk-benefit ratio shifts unfavorably and dose reduction is preferable

Additional Systemic Benefits Animal research also suggests possible benefits of using GHK-Cu for the following applications: Lung protection in injury models DNA repair signaling Anti-cancer activity Anxiolytic and analgesic effects Preservation of gut barrier integrity These are much less conclusively proven in humans compared to the previous benefits, but they are biologically plausible based on known GHK-Cu signaling pathways

Yes, GLP-1 receptors are present in the brain, including regions involved in reward, motivation, and appetite regulation