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Additional safety concerns include hypoglycemia risk when used with insulin or insulin secretagogues, potential acute kidney injury with dehydration, and with semaglutide, worsening of diabetic retinopathy in patients with pre-existing retinopathy
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Similar to other peptides, the best time to administer Ipamorelin is at night, before bedtime
Retatrutide's long-term safety has not been established, and "research use only" products sold outside the pharmaceutical supply chain add risks of contamination, incorrect concentration, and unsterile handling on top of the drug's intrinsic effects
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