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In the cytoplasm, vitamin B12 deficiency impacts the enzyme methionine synthase, with some consequences that adversely affect DNA, RNA, proteins, neurotransmitters, and phospholipids, and with some consequences that indirectly contribute to oxidative stress

doi: 10.1530/JME-17-0311 38 SabatiniDM

In adulthood, HGH helps to maintain healthy organs, bones, muscles, and skin

Safety, tolerability, manufacturing scale, reimbursement and long-term outcomes will increasingly determine which products become commercial winners

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