None of these compounds are approved by Health Canada for general therapeutic use they operate in various specific contexts
Diabetes is a chronic disease that progresses over decades
Just for the convenience of all of u, I am adding the list the I recently posted just a few days back here on LinkedIn
--- Sources Neeland et al., Changes in lean body mass with GLP-1-based therapies and mitigation strategies , Diabetes, Obesity and Metabolism (2024): Jensterle et al., Rethinking Muscle Health Assessment in GLP-1-Based Therapies for Obesity: Beyond Lean Mass , DOM (2026): Wilding et al., STEP 1 body composition exploratory analysis: LEAN-PREP randomised controlled trial protocol (2025): Function and Lean Mass Preservation With Resistance Exercise During GLP-1RA Treatment, ClinicalTrials.gov: WHO Guidelines on Physical Activity and Sedentary Behaviour: Wegovy Singapore availability and prescription status:
Tirzepatides engineered backbone activates both pathways concurrently, producing compounded effects on insulin sensitivity and glucose-dependent insulin secretion that neither agonist achieves independently
#ObesityMedicine #MetabolicHealth #PrecisionMedicine #Endocrinology #GLP1 #Tirzepatide #Semaglutide #BariatricSurgery #ChronicDisease #HealthcareInnovation #LifestyleMedicine To view or add a comment, sign in OBESITY NEWS Recent press release by Novo Nordisk highlights interesting points CHRONIC DISEASE Obesity should be approached as a chronic, progressive, and multifactorial disease, not as a matter of willpower