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For the Chc-mScarlet/Ent2-mNeonGreen pair, mutation of the Arrestin box showed a significant decrease in FRET efficiency (9.02% for WT vs

13b, and Supplementary Data 2), although many unique gene expression changes specific to mog-3(-) and fem-3(gf) mutants or mated WT hermaphrodites were also evident, which are to be expected due to the different experimental conditions in separate studies

The researchers focused on three aspects: how the brain utilises glucose (using PET scans), how cognitive functions change (memory and thinking tests), and how brain volume changes (MRI)

More significant and consistent weight loss typically becomes noticeable after several months of ongoing treatment

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