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Harvard T.H
GLP-1 medications are FDA-approved for chronic weight management in adults with obesity (BMI 30) or overweight (BMI 27-29.9) with at least one weight-related comorbidity
(18(2)) doi:10.3390/nu18020271
Some patients do make this switch under medical supervision
The first indirect pathway is GI-mediated fluid and electrolyte loss
As detailed in the current review, semaglutide appears not to increase the risk of pancreatitis (yet nevertheless it has been added to the SmPC to align with health authorities expectations on class labeling), but it is associated with more events of cholelithiasis
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