miR-138 Activates NF-b Signaling and PGRN to Promote Rheumatoid Arthritis via Regulating HDAC4
Storage and Handling Keep your BPC 157 nasal spray in good shape with proper storage: Store in the fridge (28C / 3646F) after opening Keep away from direct sunlight and heat Do not freeze freeze-thaw cycles can break down the peptide Use within 60 days of opening for best potency Keep the spray nozzle clean to prevent contamination Keep out of reach of children and pets Research Applications and Potential BPC-157 has been the focus of many scientific studies
A lyophilized powder in a sealed vial
Animal Toxicology Studies Animal toxicology studies tested doses from 0.0027 mg/lb to 9.1 mg/lb via intraperitoneal, intramuscular, intravenous, and oral routes for up to 6 weeks, finding: No acute toxic or lethal dose No gross or histologic toxicity in major organs No hepatotoxicity or nephrotoxicity Negative Ames test (no mutagenicity) Negative chromosomal aberration tests (no genotoxicity) No teratogenicity in rat pregnancy studies No local injection site irritation The LD1 (minimum lethal dose) could not be achieved despite aggressive testing
Animal studies have reported accelerated healing of gastric ulcers and intestinal injuries when BPC-157 was administered
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