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While essential AAs have been extensively studied, the roles of conditionally essential amino acids (CEAAs), cysteine (Cys), and tyrosine (Tyr) in CD pathogenesis remain comparatively underexplored

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Unlike small-molecule drugs that often have broad, systemic effects, peptides are large enough to target specific biological pathways yet small enough to penetrate tissues and reach injured areas effectively

Specifically, INF- released by CD8 + T cells downregulated the expression of SLC7A11 and SLC3A2, leading to a decrease in GSH and an increase in lipid peroxidation

Study design, and diet and treatment groups are diagrammed in Fig

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