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Kathy Bates, 77 In October 2024, Oscar-winning actress Kathy Bates opened up about her 100-pound weight loss, clarifying that while Ozempic played a role, it was far from the whole story

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Extremely low calories plus rapid weight loss means youll lose muscle and feel terrible Why Lifting Weights Matters More Than Ever Heres the brutal reality: lean tissue loss makes up 26-40% of total weight loss with GLP-1 medications

Many also have insulin resistance, Santoro notes