In a phase 2 trial, cagrilintide at a dose of 2.4 mg led to a 9.7% weight reduction by week 26
Grid search and five-fold cross-validation were then used to search for hyperparameters
C., & Stefanski, A., for the SURMOUNT-1 Investigators
"Maybe a few years ago people didnt appreciate that that would happen so quickly," he said
This dual approach helps maintain steady levels throughout the day
Adverse Effects and Long-Term Safety Concerns While GLP-1 receptor agonists have shown significant benefits, their widespread use is limited by potential side effects such as gastrointestinal distress, pancreatitis risk, and concerns over long-term metabolic effects