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A structured tirzepatide meal plan should prioritize: 80 to 120 grams of protein daily (minimum) Adequate hydration (at least 64 ounces of water) Fiber from vegetables and whole grains A quality multivitamin to cover micronutrient gaps Omega-3 fatty acids for metabolic support The tirzepatide with B12 combination has become popular because B12 supports energy production, which can offset the fatigue some people experience during rapid weight loss