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Contact your medical provider if you experience: Vomiting or diarrhea that does not improve Dizziness, fainting, or feeling like you may pass out Very little urination Confusion or extreme weakness Inability to keep fluids down Severe or worsening abdominal pain Signs of dehydration that do not improve with fluids Symptoms that become worse after a dose increase You should also reach out if you are unsure whether your symptoms are related to your medication, summer heat, dehydration, or another health concern
Therefore, in our current study, we opted to use the AlphaFold-generated MRP1 and MRP7 human structures as they include the missing gaps from the bovine MRP1 structure and TMD0
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