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Sep 9 2019;11(9):e5604

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During Salmonella Typhimurium infection, C16-carnitine localizes to regions of immune cell destruction, and C16-carnitine acts as a local immunoregulatory molecule that significantly interferes with host immune homeostasis by affecting the number and function of specific immune cell populations, such as T cells and B cells, suggesting that the accumulation of LCACs is part of the pathogen immune evasion strategy [60]

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Articular cartilage degradation in osteoarthritis

has shown minimal expression of L-carnitine synthesis pathway genes in human oocytes, and an absence of L-carnitine synthesis enzymes in cumulus cells ( The dosage of L-carnitine could explain the discrepancies between our study and Kitanos