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doi:10.2174/1874467210666170302104053 Hupalo S, Bryce CA, Bangasser DA, Berridge CW, Valentino RJ, Floresco SB

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Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas

Cell migration: In vitro studies have observed TB-500 influencing the migration of keratinocytes, endothelial cells, and fibroblasts in wound models Integrin-linked kinase (ILK) activation: Preclinical data suggest Thymosin Beta-4 activates ILK, which may play a role in cell survival signaling in experimental cardiac models Angiogenic signaling: TB-500 has been observed to stimulate endothelial cell migration and tube formation in in vitro angiogenesis assays

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For biochemical assays, each 0.5 g sample of leaf material was homogenized in 3 mL 25 mM HEPES buffer (pH 7.8) containing 0.2 mM EDTA and 2% (w/v) polyvinylpyrrolidon