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Chronobiol Int (2014) 31(5):71530

Giuseppe Benedetti

The GH/IGF-1 axis declines with age, and secretagogues can transiently raise it, but restoring a biomarker toward youthful levels has never been shown to equal restored youthful function and some GH-axis interventions carry theoretical risks that make the anti-aging framing particularly premature

This involved suspending the grown biomass directly in DMEM supplemented with FeSO 4 , MgSO 4 , MnSO 4 , and Tween 80, followed by fermentation with the matrix in the same bioreactor

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