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after initial weight loss through diet, participants received liraglutide or placebo for one year

Statistical analysis was by paired t-test for (B) and (D), and Wilcoxons sign-ranked tests for (A) and (C), as the control values were below the limit of detection (13 mol/mol Ser for MG-H1, and 18 mol/mol Ser for MG-H2b), and must therefore be considered non-Gaussian

Regulatory concerns are significant

13 Imiquimod is also effective for treating locally occurring subclinical lesions

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