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More serious but less common side effects to watch for at this dose include acute pancreatitis (symptoms: severe abdominal pain radiating to the back, nausea, vomiting), gallbladder problems (symptoms: sudden pain in the upper right abdomen, fever, jaundice), and significant hypoglycemia if combined with certain diabetes medications

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The firm says its onceaday pill uses the same active ingredient as Wegovy, but with a different formulation and delivery system, and lets providers customise doses for patients who want to avoid needles or need smaller doses to balance sideeffects

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The challenge is that lifestyle interventions alone rarely restore GLP-1 function to optimal levels in people with significant metabolic resistance