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Evidence Limitations and Interpretation Boundaries The main limitation of the current BPC-157 literature is not the absence of biological signals, but the difficulty of translating those signals into a complete and clinically meaningful mechanism

[44] In the cytosol [edit] Methylcobalamin and 5-methyltetrahydrofolate are needed by methionine synthase in the methionine cycle to transfer a methyl group from 5-methyltetrahydrofolate to homocysteine, thereby generating tetrahydrofolate (THF) and methionine, which is used to make SAMe

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