novo nordisk's wegovy reduces cardiovascular risk more than lilly's tirzepatide Which Weight-Loss Drug Is Better: or Zepbound? Eli Lilly's Mounjaro shows cardiovascular

With tirzepatide, the weight loss was nearly 2.5 times more [than semaglutide]. Garg and colleagues conducted a retrospective study of 150 adults aged 18 years or older with type 1 diabetes treated with multiple daily insulin injections or an insulin pump

Those with pre-existing chronic liver disease warrant closer surveillance, though semaglutide is not contraindicated in compensated liver disease

Int J Obes 50 , 928937 (2026)

Generally, treatment is well-tolerated

The weight loss guarantee adds a layer of accountability that most telehealth platforms avoid it signals confidence in the program and provides patients with a safety net