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Heart failure (HF) is currently considered a systemic multi-organ syndrome fundamentally driven by metabolic failure, and carnitines, a crucial metabolite in fatty acid metabolism, transport long-chain fatty acids into myocardial mitochondria to produce energy as a source of ATP generation [1] (Fig
Reconstitution refers to adding a measured volume of sterile or bacteriostatic water to the vial in order to create a solution with a known concentration, expressed as international units (IU) per millilitre (mL)
Curr Opin Cardiol (2007) 22(4):3115
The identified compounds in ASE possessed acceptable pharmacokinetic and ADMET (for absorption, distribution, metabolism, excretion and toxicity) properties
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Three distinct clinical entities have been described
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