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This trial was designed to assess the pharmacokinetics, safety and tolerability of OW s.c

The study product was well-tolerated, with only one mild adverse event reported

Improvements in renal function The mechanism underlying the renal benefits in LEADER and SUSTAIN-6 is not well understood

Acknowledgements The authors acknowledge the following grant support: A.C

Individual Variation: How quickly semaglutide GLP-1 affects appetite can differ based on personal factors such as metabolism, lifestyle, and adherence to recommended dosages

Result: Baricitinib preserved C-peptide and improved CGM-measured glycemic stability at 48 weeks