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The ability of hydroxocobalamin to rapidly scavenge and detoxify cyanide by chelation has resulted in several acute animal and human studies using systemic hydroxocobalamin doses at suprapharmacological doses as high as 140 mg/kg to support its use as an intravenous (IV) treatment for cyanide exposure
The different receptors throughout the body provide unique functions
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Identification of hub genes associated with pyroptosis in diabetic nephropathy patients using integrated bioinformatic analysis
It doesn't appear to work like most pharmaceuticals that latch on to one specific receptor
No serious adverse events have been documented in published trials, but the absence of large-scale randomized controlled trials means the full side effect profile
