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PF-06882961 was a partial agonist in recruiting Arr2 (EC 50 = 490 nM, E max = 36%), while exenatide (Arr2 EC 50 = 9.0 nM, E max = 75%) and liraglutide (Arr2 EC 50 = 20 nM, E max = 99%) were respectively 54- and 23-fold more potent with greater E max values
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Goldstein, and H
This increase could have resulted in the increase in food and water intakes of rats
However, realizing broader societal impact requires addressing fundamental cost, access, and long-term sustainability challenges
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Youve been diagnosed with multiple endocrine neoplasia syndrome type 2 (MEN 2) : This rare genetic condition predisposes individuals to certain cancers, including MTC
