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The SUSTAIN 6 trial showed that subcutaneous semaglutide reduced major adverse cardiovascular events by 26% in patients with type 2 diabetes and established cardiovascular disease (hazard ratio 0.74, 95% CI 0.58-0.95)
Additionally, GLP-1 therapies are gaining recognition as a novel approach to Alzheimers disease due to their anti-inflammatory and neuroprotective characteristics
Most people tolerate GLP-1 pills well, and not everyone will experience side effects
GLP-1 medications typically begin at low doses and titrate upward over several weeks
USA 108 , 62526257 (2011)
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