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Multiple cytokines and inflammatory factors participate in keloid formation, such as transforming growth factor 1(TGF-1), vascular endothelial growth factor (VEGF), interleukin (IL)-1, IL-6, and IL-8, as well as increased matrix metalloproteinases (MMP S ), which may promote fibroblast proliferation and migration, the inflammatory response, and collagen production 2,3,4

BMI under 25 may be considered in cases of abnormal weight gain, at the provider's discretion

What Makes It Special

It helps reduce appetite, slow stomach emptying, and promote a sense of fullnessmaking it a great option for individuals who have struggled with obesity or weight loss resistance

Whilst unpleasant burps are generally a benign side effect, certain circumstances warrant prompt medical review to exclude more serious gastrointestinal complications

Reducing body weight can improve disease activity scores, inflammatory markers, and physical function