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The co-expression of ST and RAS V12 leads to the upregulation of topoisomerase I, thereby increasing cellular susceptibility to Erastin (Dolma et al., 2003)

Patients could have adverse side effects, could be receiving something that is not the actual drug and then we're in trouble." Haddad told CBS News Miami about her side effects

These appear to be dose-dependent and typically resolve with dose reduction

People with lower body fat may find certain sites have insufficient subcutaneous tissue for a comfortable injection

By week 36, the rate slows to roughly one pound weekly