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Massive effects on gene expression

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To date, accumulating evidence supports the crucial role of ferroptosis in the onset and progression of DKD, and ferroptosis inhibition exerts a protective effect in DKD models[68, 88]

Compared with sham rats, LOsG-treated rats had higher reactive oxygen species (ROS) levels in peripheral leukocytes and pancreatic tissue while TGF signalling was upregulated

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